ASSOCIATIONS OF PRE-EXISTING CARDIOVASCULAR MORBIDITY WITH SEVERITY AND THE FATALITY RATE IN COVID-19 PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Associations of pre-existing cardiovascular morbidity with severity and the fatality rate in COVID-19 patients: a systematic review and meta-analysis

Objectives The aim of this study was to evaluate the association of pre-existing cardiovascular comorbidities, including hypertension and coronary heart disease, with coronavirus disease 2019 (COVID-19) severity and mortality.Methods PubMed, ScienceDirect, and Scopus were searched between January 1, 2020, and July 18, 2020, to identify eligible stu

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Opportunities and limits of the one gene approach: the ability of Atoh1 to differentiate and maintain hair cells depends on the molecular context.

Atoh1 (Math1) was the first gene discovered in ear development that showed no hair cell (HC) differentiation when absent and could induce HC differentiation when misexpressed.These data implied that Atoh1 was both necessary and sufficient for hair cell development.However, other gene mutations also result in loss of initially forming HCs, notably n

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Transcriptomic insights into antagonistic effects of gibberellin and abscisic acid on petal growth in Gerbera hybrida

Petal growth is central to floral morphogenesis, but the underlying genetic basis of petal growth regulation is yet to be elucidated.In this study, we found that the basal region of the ray floret petals of Gerbera hybrida was the most sensitive to treatment with the phytohormones gibberellin (GA) and abscisic acid (ABA), which regulate cell expans

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Testicular sperm aspiration has a poor effect in predicting micro-TESE outcomes in NOA patients with AZFc deletion

Abstract Background Testicular sperm aspiration (TESA) is widely used in the diagnosis and management of nonobstructive azoospermia.However, its ability for predicting microdissection testicular sperm extraction in nonobstructive azoospermia (NOA) patients with AZFc deletion remains uncertain.To investigate whether TESA affected Snap Plug the sperm

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